Xiaoyan Qin
Current research description: Investigate the biochemistry of enzymes, especially sulfotransferase, involved in conversion and metabolism of drugs or toxicants. Major focus is on the inhibition and regulation of the enzyme.
Thesis Title: Oxidative and Electrophilic Structural Modification and Catalytic Regulation of Human Hydroxysteroid Sufotransferase 2A1 (hSULT2A1)
Advisor: Michael Duffel, Ph.D.
Year of Graduation: 2014
Program: Ph.D.
Current Position: President Assistant
Current Employer/Institution: Zensung Science and Technology
Publications from Research:
Qin, X., Lehmler, H-J., Teesch, L.M., Robertson, L.W., and Duffel, M.W, 2013, Chlorinated Biphenyl Quinones and Phenyl-2,5-benzoquinone Differentially Modify the Catalytic Activity of Human Hydroxysteroid Sulfotransferase hSULT2A1, Chemical Research in Toxicology, 26:1474-85. PMCID: PMC3846294
Qin, X., Teesch, L.M. and Duffel, M.W, 2013, Modification of the Catalytic Function of Human Hydroxysteroid Sulfotransferase hSULT2A1 by Formation of Disulfide Bonds, Drug Metabolism and Disposition, 41:1094-1103. PMCID: PMC3629806
