Dr. Salem's research interests are primarily focused on self-assembling systems, the rational design of novel drug and gene delivery systems and on the development of vaccines that stimulate potent antigen-specific immune responses. Dr Salem's laboratory applies microfabrication techniques to develop novel drug and gene delivery devices and to optimize control over polymer-cell interactions. The group is currently exploring the synergistic application of polymer particle technology, CpG oligonucleotides, adenoviruses and heat shock protein therapy for generating sustained stronger immune responses against tumors.