Campus Address: 2-452 Bowen Science Building

Primary Department: Department of Neuroscience and Pharmacology

Interdisciplinary Department: Interdisciplinary Graduate Program in Human Toxicology, Interdisciplinary Graduate Program in Molecular Medicine, Interdisciplinary Graduate Program in Neuroscience, Interdisciplinary Graduate Program in Translational Biomedicine

Research Description: Dr. Strack's laboratory is interested in the roles of one of the major serine/threonine phosphatases, protein phosphatase 2A (PP2A) in normal and pathological brain function. PP2A is a diverse group of multi-subunit enzymes consisting of a constant catalytic (C) and scaffolding (A) subunit and a third variable, or regulatory (B) subunit.  Select current projects: 1) Role of PP2A in nerve growth factor signaling and neurite outgrowth, 2) Regulation of mitochondrial function and neuronal survival, 3) Structure-function analysis of PP2A holoenzymes, and 4) Regulation of catecholamine biosynthesis by PP2A.