Kiran Dhakal

kiran-dhakal.jpg
Program: 
Ph.D.
I joined Interdisciplinary graduate program in human toxicology in 2009. After completing three lab rotations, I joined Dr. Robertson’s lab in June 2010. My research area is inhalation toxicity of lower chlorinated PCBs. Taking a prototypical congener (PCB3), I’m looking at different phase II metabolites in urine in order to identify a potential biomarker metabolite for assessment of environmental exposure to lower chlorinated PCBs. Additionally, I’m also looking at genotoxicity, specifically mutation frequency in lungs, following sub-chronic inhalation of PCB3 in a rat model.
223 IREH (UI Research Park)
Kiran-dhakal@uiowa.edu
BVSc
Bachelor in Veterinary Science
Tribhuvan University Nepal
2004
MPH
Master of Public Health
Kansas State University, Manhattan, KS
2009
Advisor: 
Larry Robertson, Ph.D.
Publications: 

Dhakal K, Lehmler HJ, Teesch L, Duffel M, Robertson LW, et al. 2012. Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) as a potential biomarker of environmental exposure to lower chlorinated PCBs. Manuscript in progress.

Lai IK, Dhakal K, Gadupudi GS, Li M, Ludewig G, Robertson LW, et al. 2012. N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents. Toxicology.

John A Pickrell, Kiran Dhakal and Sharon M. Gwaltney-Brant. Respiratory System Toxicology. “Small animals Toxicology Essentials”.   ISBN: 978-0-8138-1538-1. Wiley-Blackwell publications. 2011.

Dhakal K. and Pickrell J. (2009). Comparative in vitro Estimates of Inhalation Toxicity of Selected Nannoparticles. MPH thesis. Kansas State University. Available at: http://krex.k-state.edu/dspace/bitstream/2097/1639/1/KiranDhakal2009.pdf

Dhakal K. and Pickrell J. (2009). Comparative in vitro Estimates of Inhalation Toxicity of Selected Nannoparticles. MPH thesis. Kansas State University. Available at: http://krex.k-state.edu/dspace/bitstream/2097/1639/1/KiranDhakal2009.pdf