Jaymie Voorhees

Biography

I joined the Human Toxicology Program in the fall of 2012.  My journey to toxicology began during my undergraduate time at Eastern Illinois University.  While pursuing a biological sciences degree, I decided to take part in independent research working with atrazine exposure in a watersnake population in Illinois.  This project, along with my diverse course work in biology, sparked my interest in furthering my education in toxicology.  After completing my degree in 2010, I moved to Boston to work at The Immune Disease Institute as a research technician.  The main focus of the laboratory was the diverse field of vascular biology.  Working in a medical research laboratory with talented colleagues solidified my decision to further my education in toxicology and brought me to The University of Iowa. 

I’ve always been interested in science, medicine and nature—it is only natural that I’d be interested in a career that combines all of these facets of life.  I’m very excited to see where these next few years will take me in my research career.

Research Description: In the lab, I worked on projects that focused on the development of a neuroprotective compound, P7C3, discovered by Dr. Pieper. My thesis work studied the effects organophosphate exposure in models of neurodegeneration, specifically Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and traumatic brain injury.

Dissertation TitleCognitive Impairment and Neuronal Damage in Alzheimer’s Disease are Malleable: Chlorpyrifos Exposure Exacerbates Phenotypes, while the Neuroprotective Compound P7C3 Ameliorates Effects in a Transgenic Model of Alzheimer’s Disease

AdvisorAndrew Pieper, MD, PhD

Program: Ph.D.

Current Position: Study Director II

Current Employer/Institution: Inotiv

Publications From Human Toxicology Program Research

Jaymie R Voorhees, Diane S Rohlmam, Pamela J Lein, Andrew A Pieper, Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds, Front Neurosci 2017 Jan 18;10:590, doi: 10.3389/fnins.2016.00590.

Jaymie R Voorhees, Matthew T Remy, Claire M Erickson, Laura M Dutca, Daniel J Brat, Andrew A Pieper, Occupational-like organophosphate exposure disrupts microglia and accelerates deficits in a rat model of Alzheimer's disease, NPJ Aging Mech Dis, 2019 Jan 22;5:3, doi: 10.1038/s41514-018-0033-3.

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Jaymie Voorhees